What is SS-31 Peptide Vial ?
SS-31 Peptide Vial: A Mitochondria-Targeted Antioxidant Peptide Ushering in a New Era of Anti-Aging.
SS-31 Peptide Vial (also known as Elamipretide) is a mitochondria-targeted tetrapeptide composed of four amino acids (D-Arg-dimethylTyr-Lys-Phe-NH₂). With its unique cationic and aromatic structure, it can actively cross cell membranes and selectively localize to the inner mitochondrial membrane. It was originally designed to protect mitochondrial structure, enhance energy metabolism, and counteract oxidative stress and apoptosis.
Unlike traditional antioxidants, SS-31 does not simply "scavenge" free radicals. Instead, it stabilizes mitochondrial membrane lipids-particularly cardiolipin-thereby optimizing mitochondrial function at its source and preventing excessive production of ROS (reactive oxygen species). This mechanism enables it to achieve true anti-aging effects at the cellular level.
Key Technical Specifications:
| Name | SS-31 Peptide Vial |
| CAS | 736992-21-5 |
| Applications | Mainly for Anti-Aging |
| Purity | 99.8% |
| Molecular Formula | C32H49N9O5 |
| Package | 10 Vial/Box |
| Dosage | 5mg,50mg |
| Storage | Store in a cool, dry place, away from direct sunlight |
| For research use only | Contact us for COA, HPLC, price list, and other information |
quality control
| Product Name | SS-31 Elamipretide | CAS NO. | 736992-21-5 |
| Molecular Formula | C₃₂H₄₉N₉O₅ | Molecular Weight | 639.8 |
| Sequence | DArg-2,6-DiMe- Tyr-Lys-Phe-NH2 | ||
| Quantity | 103.4g | Manufacturing Date | 2026.04.06 |
| Lot No | HB20250906 | Retest Date | 2028.04.05 |
| Test ltems | Specification | Results | |
| Appearance | White to off white powder | Conforms | |
| Purity(HPLC) | ≥98% | 99.01% | |
| Acetic acid | ≤ 22.0% | 16.20% | |
| Related Substances (Total Impurities) | ≤ 2.0 % | 0.80% | |
| Water | ≤ 8.0% | 0.90% | |
| Peptide Content | ≥ 85.0 % (on anhydrous basis) | 95.10% | |
| Acetate Content (Counter-ion) | 5.0%-12.0% | 8.20% | |
| Bacterial endotoxin | ＜10EU/mg | Conforms | |
| Heavy Metals | ≤ 20 ppm | Conforms | |
| Packaging and storage | Place in an airtight container protected from light and keep the temperature between -4℃ or -20℃. | ||
| Conclusion | The test results comply with the requirements of in-house specification. | ||
What is the Mechanism of Action of SS-31 Peptide Vial?
Mechanism of Action: Targeting Mitochondria to Protect the Cell's Energy Powerhouse at Its Source
Mitochondria are the cell's energy factories and also the primary site of free radical production. The mechanisms of SS-31 mainly include the following:
- Targeting Cardiolipin
SS-31 binds to cardiolipin, a unique phospholipid located in the inner mitochondrial membrane, preventing its oxidative damage and thereby preserving the integrity and function of the mitochondrial membrane.
- Enhancing ATP Synthesis Efficiency
By optimizing the stability of complexes within the electron transport chain (ETC), SS-31 reduces electron leakage and improves the efficiency of cellular energy metabolism.
- Reducing Excessive ROS Production
Through structural stabilization and functional optimization, SS-31 decreases the generation of reactive oxygen species (ROS) at the source, rather than relying on external free radical scavenging.
- Anti-Inflammatory and Anti-Apoptotic Effects
SS-31 inhibits mitochondria-mediated cell death pathways (such as cytochrome c release) and helps alleviate chronic inflammatory responses, contributing to the delay of degenerative diseases.
What are the Research Evidences of SS-31 Peptide Vial?
Research Evidence: Therapeutic Potential Across Multiple Diseases and Aging Conditions
In recent years, SS-31 (Elamipretide) has demonstrated significant effects in various disease models, spanning the cardiovascular system, kidneys, neurodegenerative eye disorders, and age-related muscle decline:
Cardiovascular Health
Animal studies and human clinical trials have shown that SS-31 can reduce myocardial ischemia-reperfusion injury and improve mitochondrial energy metabolism in cardiac cells. It has demonstrated potential therapeutic value in chronic heart failure.
Improvement in Muscle Function
In elderly individuals and mouse models, SS-31 significantly enhances exercise endurance, improves mitochondrial respiratory capacity, and reverses age-related muscle decline.
Degenerative Eye Diseases
Research indicates that SS-31 may improve age-related macular degeneration (AMD) and optic neuropathies. It also shows promise for treating mitochondrial diseases such as Leber hereditary optic neuropathy (LHON).
Renal Protective Effects
In models of acute kidney injury and chronic kidney disease, SS-31 has demonstrated the ability to inhibit renal tubular apoptosis and reduce oxidative stress.
What are the Differences from Traditional Antioxidants ?
|
Category |
SS-31 Peptide Vial |
Traditional Antioxidants (e.g., Vitamin C, Vitamin E, Coenzyme Q10) |
|
Site of Action |
Targets the inner mitochondrial membrane |
Systemically distributed, low targeting specificity |
|
Antioxidant Mechanism |
Reduces ROS production at the source |
Scavenges already-formed ROS |
|
Cellular Penetration |
Optimizes mitochondrial structure and improves energy metabolism |
Most cannot effectively enter mitochondria |
|
Functional Impact |
Optimizes mitochondrial structure and improves energy metabolism |
Primarily provides antioxidant effects |
|
Application Potential |
Anti-aging, neurodegeneration, cardiovascular and renal protection |
General health maintenance |
What are the Future Prospects and Safety of SS-31 Peptide Vial?
SS-31 Peptide Vial (Elamipretide) has advanced into multiple stages of clinical trials. It has received orphan drug designation from the U.S. Food and Drug Administration (FDA) for rare mitochondrial diseases, optic neuropathies, and heart failure. Although it remains under drug development, SS-31 has emerged as a major research focus in anti-aging and mitochondrial optimization, with considerable therapeutic potential.
Safety Profile
Current clinical observations suggest that SS-31 is generally well tolerated, with relatively mild reported side effects. However, the long-term safety of prolonged use still requires further investigation and confirmation through larger, long-term clinical studies.
Conclusion:
SS-31 (Elamipretide) represents the convergence of modern mitochondrial science and precision medicine. Rather than serving as a simple antioxidant, it focuses on the fundamental repair and protection of the cell's "energy core" - the mitochondria.
Its success could potentially reshape our understanding of "anti-aging," cellular health, and even the reversal of chronic diseases.
Looking ahead, SS-31 (elamipretide) lyophilized powder may be used synergistically with NAD⁺ boosters (such as NMN and NR), SOD mimetics, and ubiquitin pathway modulators to build a next-generation mitochondrial support system - paving the way toward more effective strategies for slowing the aging process.
Why choose us?
High-Purity Raw Material
We supply SS-31 Peptide Vial of superior purity, with Certificate of Analysis (COA) available for verification.
Multiple Specifications & Ready Stock
Various specifications are available and kept in stock for fast order fulfillment and immediate shipping. We also offer popular peptide stacks, including fat loss stacks, muscle growth stacks, cognitive & focus stacks, hormone/libido stacks, fat loss + muscle preservation stacks, recovery & injury support stacks, longevity stacks, and mitochondrial energy stacks.
Fast Shipping
Quick and reliable delivery ensures your products arrive safely and on time.
Related blogs
1.How Does SS-31 Impact Aging and Inflammaging?
2.What Are the Benefits of SS-31 Peptide?
3.Can SS-31 Peptide Vial Improve Mitochondrial Health and Longevity?
4.Frequently Asked Questions About Lyophilized Peptide
FAQ
Q: What makes SS-31 Peptide Vial unique?
A: SS-31 directly targets mitochondria, unlike general antioxidants that work systemically.
Q: How do you ensure the quality of the products?
A: Xi'an Ruichi Biotech can supply COA, HPLC test report and we also support the third part test like JANOSHIK or Freedom Diagnostics.
Q: Is SS-31 a peptide?
A: Yes, it is a synthetic tetrapeptide specifically designed to penetrate and act within mitochondria.
Q: What is Elamipretide?
A: Elamipretide is another name for SS-31, commonly used in scientific literature.
If you want to buy SS-31 Peptide Vial, pls feel free to contact Xi'an Ruichi Biotech Co., Ltd.
This innovative peptide has gained significant attention in anti-aging research, metabolic health, and performance optimization, making it a valuable compound for advanced applications.
E-mail: Jenny@ruichibio.com
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