1. What is PQQ?
PQQ, short for Pyrroloquinoline Quinone Disodium Salt, is a new cofactor and a biologically active compound.
PQQ is widely present in various common foods, including both plant-based and animal-based sources such as fermented soybeans (natto), green peppers, kiwis, parsley, tea, papayas, spinach, celery, and breast milk. Its concentration ranges from 3.65 to 61.0 ng/g or ng/ml. In breast milk, the total content of PQQ and its derivative IPQ is between 140-180 ng/ml, playing a crucial role in the growth and development of newborns.
2.The specific benefits of PQQ are as follows:
1. Promotes Metabolism
PQQ can stimulate mitochondrial growth and development, regulate the restoration of mitochondrial health to reduce mitochondrial autophagy damage, and increase mitochondrial activity, helping to improve energy metabolism. Mitochondria, known as the "energy factories" of cells, are essential for cell growth, metabolism, and function.

PQQ can reduce fat in the body, especially visceral and liver fat accumulation, thus preventing diet-induced obesity. PQQ works mainly by improving mitochondrial function, promoting lipid metabolism, and ultimately inhibiting fat production, reducing fat accumulation, and promoting metabolism to help eliminate toxins from the body.
2. Antioxidant Effect
PQQ has powerful antioxidant properties, capable of neutralizing free radicals and reducing oxidative stress. It helps prevent various diseases caused by free radicals, such as cardiovascular diseases and neurodegenerative diseases.
3. Improves Cognitive and Learning Ability
PQQ can increase the number and activity of mitochondria in the brain, thereby improving cognitive function and learning ability.
In an article published in Food & Function, a study by Japanese researchers titled "Pyrroloquinoline Quinone Disodium Salt Improves Brain Function in Both Younger and Older Adults" reported the results of PQQ's cognitive improvement effects on both younger and older Japanese populations.
The study included 62 healthy Japanese men and women aged between 20 and 65. Participants were divided into an intervention group and a placebo group, while maintaining their original lifestyle. They took 20mg/day of PQQ or a placebo capsule for 12 weeks. Cognitive tests, which assessed 15 brain functions, were conducted at baseline (0 weeks), 8 weeks, and 12 weeks using an online testing system developed by a company.
The results showed that, compared to the placebo group, after 12 weeks of PQQ supplementation, the composite memory and verbal memory scores increased for all participants and for older adults. After 8 weeks of PQQ supplementation, the cognitive flexibility, processing speed, and executive speed scores improved in the younger group.
This proves that PQQ not only improves brain function in older adults but also enhances brain responsiveness in younger people.
4. Promotes Nerve Growth and Repair
PQQ can promote the growth and repair of nerve cells, which plays an active role in the protection and repair of the nervous system. In cases of neurodegeneration, symptoms such as insomnia, vivid dreams, and memory loss may occur. PQQ can help improve memory and also improve sleep quality, including shortening the time to fall asleep and enhancing sleep efficiency.

5. Boosts Immunity and Regulates Inflammatory Response
PQQ can lower the levels of certain inflammatory factors, thereby inhibiting inflammation. Chronic inflammation is closely linked to the onset and development of many diseases. It also enhances the immune system and boosts the body's ability to resist diseases. In cases of low immunity, PQQ supplementation can help improve immune function.
3. Who Should Take PQQ Supplements?
In general, PQQ is especially suitable for people with weakened immunity, those prone to illness, people with high blood pressure, or those with sensitive constitutions. It is specifically beneficial for the following groups:
1. Older Adults
As we age, the amount of PQQ in the body gradually decreases. Middle-aged and elderly people can benefit from PQQ supplements to help maintain cell health and metabolic function.
2. People Needing Enhanced Antioxidant Protection
With its powerful antioxidant effects, PQQ is ideal for individuals who need to boost their antioxidant capacity and protect cells from oxidative damage.
3. People Needing Increased Energy and Metabolism
PQQ is known to promote mitochondrial function and increase cellular energy production. It is suitable for people who need to improve their energy levels and metabolic function.
4. People Concerned About Cardiovascular Health
Some studies suggest that PQQ may help maintain cardiovascular health, providing benefits for individuals at higher risk of cardiovascular diseases.
5. People Pursuing a Healthy Lifestyle
For those who focus on health and lead a healthy lifestyle, PQQ supplements can serve as an auxiliary nutritional supplement to help maintain overall body health and vitality.
If you want to buy Pyrroloquinoline Quinone Disodium Salt and would like to learn more other products, please feel free to contact Xi'an Ruichi. We look forward to hearing from you.
Email: Jenny@ruichibio.com




