Pyrroloquinoline Quinone Disodium

Pyrroloquinoline quinone disodium salt, whose core active component is pyrroloquinoline quinone (PQQ, CAS: 122628-50-6), is a unique aromatic tricyclic o-quinone compound. It is often referred to as the "king of immunity" in the biological field and is widely recognized by the scientific community as one of the most potent natural antioxidants known to date.

Thanks to its outstanding antioxidant capacity, PQQ exhibits a wide range of important physiological functions in the body, including protecting mitochondria, promoting growth, regulating energy metabolism, influencing neurological function, improving cardiac performance, and helping manage diabetes and its related complications.

Pyrroloquinoline quinone (PQQ) and PQQ disodium salt refer to the same core compound, but they differ in their specific chemical forms and applications. In the context of dietary supplements or research, PQQ disodium salt is typically implied unless otherwise specified.

PQQ in its base form-also known as PQQ free acid-tends to have lower stability and poorer water solubility compared to its disodium salt form.

PQQ disodium salt is the form in which PQQ is bound to two sodium ions (Na⁺). This form offers enhanced stability and improved water solubility, making it more suitable for use in dietary supplement formulations and other applications where high solubility is required.

Despite these differences, both forms exhibit similar physiological effects and potential health benefits, particularly in terms of antioxidant activity and mitochondrial support.

1. Promotes Mitochondrial Metabolism

One of the key functions of PQQ is its direct action on mitochondria-the essential organelles responsible for energy production within cells. As a result, PQQ helps promote energy generation.

In addition, PQQ's powerful antioxidant properties help protect mitochondria from damage. However, PQQ does more than just shield mitochondria from oxidative stress-it also stimulates the spontaneous formation of new mitochondria in aging cells. This process is known as mitochondrial biogenesis.

This unique effect is often described as a "fountain of youth" for mitochondrial function.

2. Antioxidant Activity
PQQ possesses strong antioxidant properties. It effectively scavenges free radicals in the body, reduces oxidative damage, and may help lower the risk of diseases such as tumors and heart disease.

3. Immune System Regulation
PQQ can stimulate cell growth, particularly by activating B cells and T cells, thereby enhancing overall immune function.

4. Protection Against Liver Damage
PQQ has been shown to significantly reduce serum bilirubin and alanine aminotransferase (ALT) levels, helping maintain normal liver function and support recovery from liver injury.

5. Support for Neurological Health
PQQ promotes the synthesis of nerve growth factors in the body, helping regulate various neurological conditions. It may assist in repairing nerve fibers, activating neurons, and stimulating dormant nerve cells, thereby helping prevent neurodegenerative disorders and improve memory.

6. Enhances Amino Acid Absorption
PQQ serves as a cofactor for quinoproteins and participates in electron transfer within the respiratory chain. It helps promote the absorption of amino acids, which are essential building blocks for cellular fluids and protein synthesis.

Xi'an Ruichi Biotech Co., Ltd. is an innovative life science company providing dietary supplements, custom synthesis. We also provide OEM and private label services, including custom logo and packaging options, to meet your branding needs. Dosage forms including powder, capsules,softgels, tablets. As an FDA-registered manufacturer, we are committed to improving human health through consistent quality, regulatory compliance, and sustainable growth. We manufacture and source a broad portfolio of dietary supplements and health ingredient raw materials for global markets.

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