5-Amino-1-MQ 60 Capsules

Most NAD⁺-focused products rely on direct precursor supplementation (such as NMN or NR). While these approaches aim to increase NAD⁺ availability by supplying additional building blocks, they do not address upstream metabolic regulation that can limit NAD⁺efficiency-especially in aging tissues.

NNMTi offers a complementary and mechanistically distinct strategy by targeting the enzyme that regulates nicotinamide (NAM) utilization within the NAD⁺salvage pathway.

As NNMT expression increases with skeletal muscle aging, excessive methylation of NAM can reduce the pool of NAD⁺ precursors and disrupt cellular energy metabolism. Simply adding more precursors may not fully compensate for this imbalance.

NNMTi focuses on optimizing the body's own NAD⁺ salvage pathway, helping to maintain metabolic efficiency rather than overwhelming the system with additional substrates.

• Strategic Advantages for Formulation
• Complements NAD⁺ precursor ingredients
• Supports metabolic balance and cellular energy homeostasis
• Particularly relevant for healthy aging and muscle vitality formulations
• Differentiated mechanism for next-generation NAD⁺ support

NNMTi is intended for nutraceutical and functional health applications. It is not intended to diagnose, treat, cure, or prevent any disease.

Certification of Analysis:

High Purity – NNMTi is produced using refined manufacturing processes to achieve high purity, which ensures better bioavailability.

Targeted Action – NNMTi specifically targets the NNMT enzyme, effectively inhibiting its activity and modulating nicotinamide metabolic pathways.

Stability – NNMTi demonstrates excellent stability, maintaining its activity and effectiveness under various environmental and storage conditions.

Development Potential – Thanks to its unique properties, NNMTi has attracted widespread attention and holds broad prospects for research and

5-Amino-1MQ functions primarily as an inhibitor of NNMT (Nicotinamide N-methyltransferase), a key regulator of cellular metabolism.

By inhibiting NNMT, it may:

Increase intracellular NAD+ levels

Enhance energy metabolism efficiency

Reduce fat accumulation signals

Improve metabolic flexibility

This mechanism positions 5-Amino-1MQ as a promising compound in metabolic health and weight management research.

NNMTi is a potent and selective nicotinamide N-methyltransferase (NNMT) inhibitor with an IC₅₀ of 1.2 μM, designed to modulate NNMT activity at the substrate-binding site. NNMT plays a key role in cellular metabolism and NAD⁺ pathway regulation, particularly in aging skeletal muscle.

Preclinical studies show that NNMTi supports myoblast differentiation, enhances muscle stem cell regeneration, and is associated with improved muscle strength, body composition, and metabolic balance. NNMTi is well suited for formulations targeting healthy aging, muscle vitality, and NAD⁺metabolism support.

For research and nutraceutical applications only.

In the scientific literature, 5-Amino-1MQ has been utilized as an experimental research compound to investigate NNMT-associated metabolic pathways and downstream cellular responses in non-clinical models.

- NNMT-mediated nicotinamide methylation pathways

- NAD+-associated metabolic regulation

- Cellular energy utilization and metabolic flux dynamics

- GLUT4-associated glucose transport signaling (experimental context)

- Stem cell-related transcriptional markers in model systems

All applications remain restricted to controlled laboratory research environments.

Our OEM formula of 5-Amino-1MQ capsules for your reference.

MATERIAL AMOUNT PER CAPSULE

5-Amino-1MQ Capsule 50 mg

Other Ingredients Gelatin (capsule shell), Microcrystalline Cellulose, Magnesium Stearate, Silica.

OEM formula activates:

*nicotinamide N-methyltransferase

*NAD+ Activator

*NNMT Inhibitor

*customized capsule shell (size,color,material)

*customized lable (PVC,Synthetic paper)

*customized dosage(20mg,50mg)

*customized bottle( size, color, material)

Capsule size for your reference

Test for 5-Amino-1MQ:

Xi'an Ruichi Biotech Co., Ltd. is an innovative life science company providing dietary supplements, custom synthesis. We also provide OEM and private label services, including custom logo and packaging options, to meet your branding needs. Dosage forms including powder, capsules, softgels, tablets. As an FDA-registered manufacturer, we are committed to improving human health through consistent quality, regulatory compliance, and sustainable growth. We manufacture and source a broad portfolio of dietary supplements and health ingredient raw materials for global markets.

Quality is embedded in every stage of our operations. All manufacturing activities are conducted under strict supervision, following validated processes and standardized procedures. Our facilities operate in full compliance with GMP requirements, ensuring that every product meets international quality and safety standards. We maintain a comprehensive system of documented SOPs, aligned with GMP guidelines and ISO 9001:2015 certification, to support reliability, traceability, and continuous improvement.

Our quality management system integrates ISO 9001:2015 and GMP standards, enabling us to deliver products and services that meet the expectations of global pharmaceutical and nutraceutical markets. All products are tested in accordance with leading pharmacopeial standards, including CP, BP, EP, and USP. Every batch is freshly manufactured, with a typical shelf life of 2–3 years, ensuring optimal stability and performance.

To ensure that customers receive their goods smoothly,we supply all kinds of couriers according to different needs.Like DHL, FedEx, UPS, EMS, TNT, by Sea, by Air.

We can provide customized packaging according to your requirement.

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